Products We Love

Supplements

6 Products

We only recommend supplements with clinical evidence behind them. Every product below has peer-reviewed research supporting its mechanism and efficacy — not just marketing claims.

Top Pick

Longevity · Cellular Energy

Resveracel

Thorne

Combines NR (nicotinamide riboside) with resveratrol and quercetin to support NAD+ production and mitochondrial function. NAD+ declines ~50% between age 40–60 and is central to cellular energy, DNA repair, and sirtuin activation.

Thorne is one of the only supplement brands with NSF Certified for Sport status and pharmaceutical-grade manufacturing standards.

Sleep · Stress · Hormones

Magnesium Glycinate

Pure Encapsulations

Magnesium is cofactor in over 300 enzymatic reactions — including cortisol regulation, testosterone synthesis, and sleep-wake cycle regulation. Glycinate form has superior bioavailability and doesn't cause GI issues. Most adults are deficient.

More bioavailable than oxide or citrate forms. Supports deep sleep, reduces cortisol response, and plays a direct role in testosterone production.

Performance · Recovery

Creatine Monohydrate

Momentous

The most well-researched performance supplement in existence — over 500 human clinical trials. Increases phosphocreatine stores, improves strength and power output, supports lean mass preservation on GLP-1 protocols, and has emerging evidence for cognitive function and neuroprotection.

5g daily is the dose with the most evidence. Momentous uses Creapure — the purest form available. No fillers, no proprietary blends.

Omega-3 · Inflammation

Omega-3 w/ CoQ10

Designs for Health

High-potency EPA/DHA (2g+ per serving) with ubiquinol CoQ10 for mitochondrial energy production. Omega-3s reduce inflammatory markers (IL-6, CRP, TNF-α), support cardiovascular health, and improve hormone receptor sensitivity — particularly relevant in HRT protocols.

Third-party tested for heavy metals and oxidation. The combination of EPA/DHA with CoQ10 addresses two of the most common deficiencies in hormonally compromised adults.

Thyroid · Immune

Selenium + Iodine Complex

Life Extension

Selenium is essential for T4-to-T3 conversion and thyroid peroxidase function. Iodine is required for thyroid hormone synthesis. Deficiency in either disrupts the entire thyroid axis. Critical for patients on thyroid protocols and those with Hashimoto's.

Selenium has also shown clinical benefit in reducing thyroid antibody levels in Hashimoto's patients in multiple RCTs — one of the few supplements with direct autoimmune evidence.

Vitamin D · Hormones

Vitamin D3 + K2

Thorne

Vitamin D3 is a steroid hormone precursor — not a vitamin. Deficiency is associated with low testosterone, insulin resistance, immune dysfunction, depression, and poor sleep. K2 ensures calcium is directed to bones rather than arterial walls. Most people on hormone protocols are deficient.

D3 without K2 is an incomplete protocol. This combination ensures proper calcium metabolism. Target serum levels of 60–80 ng/mL for optimal hormone function.

Wearables & Tracking

3 Products

The data your wearable captures is only useful if you know how to interpret it in the context of your hormone protocol. These are the devices we use and recommend — and what to look for in the numbers.

Top Pick

Recovery · HRV · Sleep

WHOOP 4.0

WHOOP

Continuous HRV, RHR, respiratory rate, skin temperature, and sleep staging. WHOOP's strain and recovery model is the most actionable framework for understanding how your body is responding to training, stress, and protocol changes. HRV is one of the best real-time markers of autonomic health and hormonal recovery.

HRV directly correlates with cortisol and testosterone levels. Watching HRV trend upward as your hormone protocol optimizes is one of the most validating data experiences available.

Sleep · Readiness · HRV

Oura Ring Gen 4

Oura

The most accurate sleep staging ring available. Tracks HRV, RHR, SpO2, skin temperature, respiratory rate, and sleep architecture with clinical-grade accuracy. The temperature sensor is particularly useful for women tracking hormonal cycle patterns and identifying disruptions.

The temperature data is uniquely valuable for women on HRT — you can see the physiological effects of estrogen optimization reflected in your skin temperature trend before you feel them.

Blood Glucose · Metabolic

Levels CGM Program

Levels Health

Continuous glucose monitoring for non-diabetics. Seeing real-time glucose responses to food, exercise, sleep, and stress is transformative for understanding metabolic health — particularly for patients on GLP-1 protocols or addressing insulin resistance. One of the most data-rich interventions available without a clinical prescription.

Insulin resistance and glucose dysregulation are among the most common drivers of hormonal imbalance. CGM makes the invisible visible — and changes behavior faster than any advice can.

Sleep

3 Products

Sleep is the foundation. These are the tools most consistently recommended by our clinical team and backed by the most evidence for improving sleep quality and architecture.

Top Pick

Sleep · Temperature

Pod 4 Ultra

Eight Sleep

Active temperature control throughout the night, adapting to your sleep stages and temperature needs in real time. Core body temperature drop of 1–2°C is required to initiate and maintain deep sleep. The Pod series is the most well-researched bed cooling system, with peer-reviewed data on sleep stage improvement.

Temperature is the single most underrated sleep lever. Eight Sleep's automatic temperature adjustment consistently improves deep sleep time — often dramatically in the first week.

Sleep · Light Blocking

Pro Blackout Sleep Mask

Manta Sleep

Complete light elimination with zero pressure on the eyes — critical for melatonin production and deep sleep. Even small amounts of light exposure during sleep suppress melatonin and fragment sleep architecture. This is one of the simplest and most evidence-backed sleep interventions available.

Blackout conditions increase melatonin production by up to 50% compared to ambient light environments. At $35, it's the highest ROI sleep intervention on this list.

Sleep · Relaxation

Magnesium Breakthrough

BiOptimizers

Seven forms of magnesium in one formula — covering the full spectrum of magnesium's physiological roles including GABA activation (calming), muscle relaxation, cortisol regulation, and sleep onset. Particularly effective for people who wake at 3–4am due to cortisol dysregulation.

The GABA-activating properties of magnesium glycinate and threonate directly support sleep onset and maintenance — particularly important for peri/menopausal women with disrupted progesterone.

Lab Testing

3 Services

For members who want to go deeper on their own — or supplement what's ordered through PepLab — these services allow you to order comprehensive labs directly, without a physician referral.

Top Pick

Comprehensive Panels

Marek Health

Direct-to-consumer lab ordering with physician review. Offers one of the most comprehensive hormone panels available — including free testosterone, SHBG, sensitive estradiol, complete thyroid, DHEA-S, cortisol, and dozens of additional markers. Results in 24–48 hours from any LabCorp location.

Marek offers the most affordable comprehensive hormone panel we've found without sacrificing clinical depth. Their physician review team is experienced in optimization, not just disease treatment.

Functional Lab Testing

Function Health

Peter Attia-backed comprehensive health testing platform. 110+ biomarkers across hormones, metabolic, cardiovascular, immune, and nutrient status. Annual membership model with physician oversight. One of the most thorough consumer health testing services available.

The breadth of Function's panel makes it exceptional for establishing a true metabolic and hormonal baseline before beginning any PepLab protocol.

At-Home Testing

Everly Health

At-home hormone and wellness testing with fingerstick or saliva collection. Convenient for initial screening, follow-up monitoring, and tracking between physician-ordered panels. Results delivered digitally with clinical interpretation. CLIA-certified lab partners.

Everly's at-home hormone panels are excellent for ongoing monitoring between formal labs — lower cost, no visit required, results in 2–5 days.

Fitness & Recovery

3 Products

Exercise is a hormonal intervention. These are the tools that most directly support the physical component of any PepLab protocol — particularly important for preserving lean mass on GLP-1 protocols.

Strength · Body Composition

Adjustable Dumbbell Set

Bowflex SelectTech

Resistance training is the most evidence-backed intervention for preserving lean mass, improving insulin sensitivity, and boosting testosterone and growth hormone response. This adjustable set replaces 15 pairs of dumbbells — the no-excuse solution for home strength training on a GLP-1 or HRT protocol.

Resistance training 3x/week is a clinical requirement on any GLP-1 protocol if you want to preserve muscle. There's no substitute for progressive overload.

Recovery · Red Light

Mito Red Panel

Mito Red Light

Red and near-infrared light therapy has emerging evidence for mitochondrial function, tissue repair, testosterone production, and inflammation reduction. The mechanism — photobiomodulation via cytochrome c oxidase stimulation — is well-characterized in the literature. 10 minutes daily, 3–5x per week.

Early studies suggest red light therapy applied to the testes increases testosterone. Separate from that, the anti-inflammatory and mitochondrial effects have strong mechanistic backing for recovery and energy.

Zone 2 · Cardio

Concept2 RowErg

Concept2

Zone 2 training is the most evidence-backed exercise modality for mitochondrial biogenesis, metabolic health, and cardiovascular longevity. Rowing provides full-body, low-impact Zone 2 in a small footprint. The Concept2 is the gold standard — used in clinical research and virtually every serious training facility worldwide.

30–45 minutes at 65–75% max HR, 3–4x per week, is the Zone 2 protocol endorsed by virtually every longevity physician. Rowing delivers it without joint stress.

Books & Resources

4 Titles

The books our team has read, referenced, and recommends to every patient who wants to understand the science behind their protocol.

Must Read

Longevity · Medicine

Outlive: The Science & Art of Longevity

Peter Attia, MD

The most comprehensive lay-accessible guide to longevity medicine available. Covers exercise, nutrition, sleep, mental health, and early disease detection as pillars of extending healthspan — not just lifespan. The hormone chapter alone is worth the price of the book.

The framework in Outlive is the closest thing to PepLab's clinical philosophy in book form. Required reading before your first physician consult.

Women's Hormones

The Hormone Cure

Sara Gottfried, MD

Harvard-trained OB/GYN Dr. Sara Gottfried's definitive guide to female hormone optimization. Covers estrogen, progesterone, testosterone, thyroid, cortisol, and insulin — with practical protocols for each imbalance. Data-driven, clinically grounded, and written for the intelligent layperson.

Dr. Gottfried's approach mirrors our clinical philosophy — root cause, comprehensive testing, and personalized protocols over symptom management.

Sleep Science

Why We Sleep

Matthew Walker, PhD

The most widely read synthesis of sleep science. Walker makes the case — backed by hundreds of studies — for why sleep is the single most important health behavior. The chapters on hormones, testosterone, immune function, and longevity are directly relevant to every PepLab patient.

After reading this, you will never deprioritize sleep again. The hormonal data alone — particularly the testosterone findings — is enough to change behavior permanently.

HRT · Women's Health

Estrogen Matters

Avrum Bluming, MD & Carol Tavris, PhD

The definitive rebuttal to the Women's Health Initiative study that scared a generation of women away from HRT. Bluming and Tavris walk through the science, the media distortion, and the current evidence — making the case that appropriately prescribed HRT is safe and beneficial for most women.

Essential reading for any woman who was told HRT was dangerous. The science has changed. This book explains why — and what you should actually know.

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Products we
actually use.

Member discounts on
everything above.